Sedating anti histamine

Drowsiness is one of the major side effects of some antihistamines, such as diphenhydramine (Benadryl) and doxylamine succinate (the antihistamine found in Nyquil).And because of their powerful sedating qualities, antihistamines are also the active ingredients found in numerous over-the-counter sleep aids. The story begins with histamines, which are chemical compounds that play a couple of roles in the body, though they're best known for their involvement in the body's local immune responses.They also make blood vessels more permeable, allowing proteins and white blood cells to seep into the damaged or infected tissue.But there are side effects to this healing process.

It's stored in cells called mast cells, in almost all tissues of the body, and is released when the body reacts to a foreign substance (known as an allergen).Many people find the worst symptom of their eczema is severe itching.Scratching relieves the itch, but also makes the inflammation and the itching worse because it causes more inflammatory substances to be released within the skin.These were some of the first antihistamines scientists developed. They also work in the part of the brain that controls . One of the most common side effects of first-generation antihistamines is feeling sleepy.For this reason, they are sometimes used to help people who have trouble sleeping (insomnia).

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For example, when you're fighting a cold (the rhinovirus), histamines widen the blood vessels in your nasal cavity, causing nasal congestion.

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